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Related Experiment Video

Updated: Jun 25, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

[Allergic contact dermatitis to cosmetics].

C Laguna¹, J de la Cuadra, B Martín-González

¹Servicio de Dermatología, Hospital General Universitario de Valencia, Valencia, España. cecipru@comv.es

Actas Dermo-Sifiliograficas

|March 10, 2009

Summary

This summary is machine-generated.

Cosmetic contact dermatitis is common, with preservatives like methylisothiazolinone and paraphenylenediamine being frequent culprits. Hair dyes and soaps were the most implicated products in this 7-year study.

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Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

Published on: September 26, 2022

Area of Science:

Dermatology
Allergology
Cosmetic Science

Context:

Cosmetic contact dermatitis is a prevalent issue, often underestimated in the general population.
Understanding specific cosmetic allergens is crucial for diagnosis and prevention.

Purpose:

To identify common allergens causing contact dermatitis from cosmetic products.
To determine the frequency of these allergens and implicated cosmetic products over a seven-year period.

Summary:

A retrospective study analyzed 202 cases of cosmetic contact dermatitis diagnosed between 2000 and 2007.
Methylisothiazolinone (19%), paraphenylenediamine (15.2%), and fragrance mixtures (7.8%) were the most frequent allergens.
Hair dyes (18.5%), gels/soaps (15.7%), and moisturizers (12.7%) were the most commonly implicated products.

Impact:

Identifies key cosmetic allergens, aiding dermatologists in diagnosis.
Highlights common product categories responsible for allergic reactions.
Suggests a need for collaboration between physicians and manufacturers to identify novel allergens.