Phenoxazinone synthase: what's in a name?

Marilize Le Roes-Hill1, Candice Goodwin, Stephanie Burton

  • 1Biocatalysis and Technical Biology Group, Department of Chemical Engineering, University of Cape Town, Private Bag 1, Rondebosch, 7701, Cape Town, South Africa.

Summary

Phenoxazinone synthases (PHS) are re-evaluated, revealing their connection to copper proteins and diverse roles in bacteria. This challenges traditional classification and suggests potential in novel antibiotic development.

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