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Quality of life in children with end-stage renal disease: does treatment modality matter?

Wai-Ming Lai1

  • 1Paediatric Nephrology Center, Department of Paediatrics and Adolescent Medicine, Princess Margaret Hospital, Hong Kong SAR, PR China. laiwm2@ha.org.hk

Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis
|March 10, 2009
PubMed

Insights

Health-related quality of life (HRQOL) is lower in children with end-stage renal disease (ESRD). Further research is needed for ESRD-specific HRQOL instruments in pediatric patients.

Area of Science:

  • Pediatric Nephrology
  • Quality of Life Research

Background:

  • Health-related quality of life (HRQOL) is crucial for assessing pediatric well-being in end-stage renal disease (ESRD).
  • Generic HRQOL instruments, like the Pediatric Quality of Life Inventory, are currently used due to a lack of ESRD-specific tools for children.

Purpose of the Study:

  • To highlight the importance of HRQOL in children with ESRD.
  • To identify the need for a pediatric ESRD-specific HRQOL instrument.

Main Methods:

  • Review of existing literature on HRQOL in pediatric ESRD patients.
  • Analysis of HRQOL scores in children with ESRD compared to healthy controls.

Main Results:

  • Children with ESRD demonstrate significantly lower HRQOL scores compared to healthy children.
  • Limited studies indicate a substantial impact of ESRD on children's quality of life.

Conclusions:

  • A significant decline in HRQOL is observed in children suffering from ESRD.
  • Development of a pediatric ESRD-specific instrument is essential to differentiate HRQOL across various treatment modalities (hemodialysis, peritoneal dialysis, kidney transplant).

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