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Cancer Therapies

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

Cancer Therapies

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

Cancer

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.

Cancer-Critical Genes I: Proto-oncogenes

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...

Cancer-Critical Genes I: Proto-oncogenes

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...

What is Cancer?

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...

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Related Experiment Video

Updated: Jun 25, 2026

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Published on: April 22, 2019

[Oncology].

Matti S Aapro¹

¹Institut multidisciplinaire d'oncologie (IMO), Clinique de Genolier, 1272 Genolier. maapro@genolier.net

Revue Medicale Suisse

|March 11, 2009

Summary

Medical oncology saw twelve major advances last year, including new breast cancer treatments like tamoxifen and hormonal therapies. Other breakthroughs include improved survival for lung and pancreas cancer patients and reduced melanoma recurrence.

Area of Science:

Oncology
Medical Research

Context:

The American Society for Clinical Oncology (ASCO) identified twelve significant advancements in medical oncology.
Recent research highlights progress in treating various cancers, including breast, lung, pancreas, melanoma, and chronic lymphocytic leukemia.

Purpose:

To summarize key breakthroughs in medical oncology from the past year.
To inform clinicians and researchers about significant treatment advancements and their potential impact.

Summary:

Extended use of tamoxifen or aromatase inhibitors benefits endocrine-responsive breast cancer. Zoledronic acid reduces recurrence risk in premenopausal women on hormonal suppression. Bevacizumab combined with paclitaxel is indicated for metastatic breast cancer.
Cetuximab improves survival in non-small cell lung cancer patients when added to chemotherapy. Adjuvant gemcitabine doubles disease-free survival in pancreas cancer. Adjuvant pegylated interferon reduces melanoma recurrence by 18%.

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Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

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Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

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Bendamustine shows significant activity in chronic lymphocytic leukemia. The HPV vaccine, approved for cervical cancer, may prevent oral cancers. Oral contraceptives are linked to reduced ovarian cancer risk.

Impact:

These advances offer improved treatment options and outcomes for patients across multiple cancer types.
The findings underscore the rapid progress in cancer therapies, potentially leading to better patient survival and quality of life.
Continued research and application of these advancements are expected to further enhance cancer care and prevention strategies.