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Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
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Male Sexual Response: Erection & Ejaculation01:17

Male Sexual Response: Erection & Ejaculation

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Rigidity and myotonia are distinct abnormalities of muscle tone that affect resistance and relaxation during movement. Although both involve altered muscle contraction, they arise from different neurological and muscular mechanisms.CharacteristicsRigidity is characterized by uniform resistance to passive movement across the entire range, independent of speed, affecting flexors and extensors equally. It may appear as lead-pipe rigidity (smooth, constant resistance) or cogwheel rigidity...
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Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis
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Sexual dysfunction in multiple sclerosis.

Thomas M Kessler1, Clare J Fowler, Jalesh N Panicker

  • 1Department of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, University College London Hospitals, UCL NHS Foundation Trust, UCL Institute of Neurology, London, UK. tkessler@gmx.ch

Expert Review of Neurotherapeutics
|March 11, 2009
PubMed
Summary
This summary is machine-generated.

Sexual dysfunction affects many adults with multiple sclerosis, impacting desire, arousal, and orgasm. Management requires addressing physical, psychological, and neurological factors.

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Area of Science:

  • Neurology
  • Sexual Medicine
  • Chronic Disease Management

Background:

  • Multiple sclerosis (MS) is a chronic neurological disorder impacting young adults.
  • Sexual dysfunction is a prevalent yet underestimated symptom in MS, affecting a high percentage of men and women.
  • Dysfunctions span reduced libido, arousal issues (including erectile dysfunction), and ejaculatory/orgasmic problems.

Purpose of the Study:

  • To review the scope and types of sexual dysfunction in individuals with multiple sclerosis.
  • To explore the multifactorial causes of sexual dysfunction in MS, encompassing primary, secondary, and tertiary factors.
  • To summarize current understanding and management approaches for sexual dysfunction in MS.

Main Methods:

  • Literature review of studies on sexual dysfunction in multiple sclerosis.
  • Categorization of sexual dysfunction based on the sexual response cycle.
  • Analysis of contributing factors: neurological lesions, physical disability, and psychological issues.

Main Results:

  • High prevalence of sexual dysfunction in MS: 50-90% of men and 40-80% of women.
  • Dysfunctions include decreased libido, erectile dysfunction, and difficulties with arousal, ejaculation, and orgasm.
  • Causes are complex, involving direct neurological impact, secondary physical limitations, and tertiary psychological distress.

Conclusions:

  • Sexual dysfunction is a major concern for individuals with multiple sclerosis.
  • A holistic management approach is crucial, addressing physiological, physical, and psychological aspects.
  • Pharmacotherapy is currently limited, primarily to erectile dysfunction treatment.