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Cancer Stem Cells and Tumor Maintenance

Early diagnosis and treatment can often cure cancer. However, even with treatment, residual cells called cancer stem cells (CSC) might remain, often causing tumor recurrence. These cancer stem cells possess the potential for self-renewal and multi-lineage differentiation and are often responsible for the therapeutic resistance displayed in most cancers.
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Related Experiment Video

Updated: Jun 25, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
05:39

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

[Differentiated thyroid cancers].

S Gorgone1, A Campennì, E Calbo

  • 1Università degli Studi di Messina, Facoltà di Medicina e Chirurgia, Cattedra di Chirurgia Generale.

Il Giornale Di Chirurgia
|March 11, 2009
PubMed
Summary
This summary is machine-generated.

This study reviews well-differentiated thyroid cancer epidemiology and diagnosis. Total thyroidectomy with central compartment lymph node removal is the preferred treatment, potentially followed by radiotherapy.

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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
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Last Updated: Jun 25, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

Area of Science:

  • Endocrinology
  • Oncology
  • Surgical Pathology

Context:

  • Thyroid cancer is a significant endocrine malignancy.
  • Well-differentiated thyroid cancers (WDTC) represent the majority of cases.
  • Understanding WDTC epidemiology and etiology is crucial for effective management.

Purpose:

  • To review the epidemiology, etiology, and diagnosis of well-differentiated thyroid cancers.
  • To present a case series and long-term experience in treating WDTC.
  • To discuss current optimal treatment strategies for WDTC.

Summary:

  • The authors provide a comprehensive review of well-differentiated thyroid cancer, covering epidemiology, etiology, and diagnostic approaches.
  • Their extensive experience with a case series informs their treatment recommendations.
  • Current preferred management involves total thyroidectomy with central compartment lymphadenectomy, potentially augmented by radioactive iodine therapy.

Impact:

  • This review offers insights into the management of a common endocrine cancer.
  • The findings support current surgical and oncological treatment standards for WDTC.
  • Highlights the importance of surgical expertise in managing thyroid cancer patients.