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Meningoencephalitis and meningitis due to an adenovirus type 5 in two immunocompetent adults
M Soeur1, A Wouters, A de Saint-Georges
1Centre Hospitalier Molière-Longchamp, Department of Internal Medicine, Brussels, Belgium.
Acta Neurologica Belgica
|January 1, 1991
Abstract:
Two unrelated patients, previously in good health, were admitted to hospital in the course of the same week, one for meningoencephalitis and the other for meningitis. In both of them, an adenovirus type 5 was cultivated on the cerebrospinal fluid. The evolution was benign in both cases. No similar observation has been found in the literature.
Insights
Adenovirus type 5 caused meningitis and meningoencephalitis in two healthy patients. Both recovered fully, and this specific adenovirus link to these neurological conditions is novel.
Area of Science:
- Neurology
- Virology
- Infectious Diseases
Background:
- Meningitis and meningoencephalitis are serious central nervous system infections.
- Adenoviruses are common viruses, typically causing respiratory or gastrointestinal illness.
Observation:
- Two previously healthy individuals presented with distinct neurological conditions: meningitis and meningoencephalitis.
- Cerebrospinal fluid analysis in both patients revealed the presence of adenovirus type 5.
Findings:
- Adenovirus type 5 was identified as the causative agent in both meningitis and meningoencephalitis cases.
- The clinical course for both patients was benign, with complete recovery.
Implications:
- This report highlights a rare association between adenovirus type 5 and severe neurological infections.
- Further research may be warranted to understand the pathogenesis and prevalence of adenovirus-induced neurological disease.