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Sjögren's syndrome in patients with multiple sclerosis
K Ellemann1, E Krogh, P Arlien-Soeborg
1Department of Neurology, Hvidovre Hospital, Copenhagen, Denmark.
Acta Neurologica Scandinavica
|July 1, 1991
Summary
This study found that 10% of women with multiple sclerosis (MS) also had Sjögren syndrome. Dry eye symptoms in MS patients warrant further diagnostic investigation for Sjögren syndrome.
Area of Science:
- Neurology
- Ophthalmology
- Rheumatology
Background:
- Multiple sclerosis (MS) is a chronic neurological disease.
- Sjögren syndrome is an autoimmune disorder affecting exocrine glands, often causing dry eyes and mouth.
- The co-occurrence of MS and Sjögren syndrome requires investigation.
Purpose of the Study:
- To evaluate the prevalence of Sjögren syndrome in female patients diagnosed with multiple sclerosis.
- To determine if dry eye symptoms in MS patients are indicative of Sjögren syndrome.
Main Methods:
- Clinical evaluation of twenty female patients with clinically diagnosed multiple sclerosis.
- Assessment for the presence of Sjögren syndrome and associated symptoms.
Main Results:
- Two out of twenty female patients (10%) presented with clinical Sjögren syndrome.
- The prevalence of Sjögren syndrome in this MS cohort was not significantly different from the general population.
- Dry eye symptoms were observed in multiple sclerosis patients.
Conclusions:
- A subset of multiple sclerosis patients may have an underlying Sjögren syndrome.
- Dry eye symptoms in patients with multiple sclerosis should prompt diagnostic evaluation for Sjögren syndrome.
- Early diagnosis and management of co-existing conditions can improve patient outcomes.