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Updated: Jun 25, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Traumatic endophthalmitis caused by Enterococcus raffinosus and Enterobacter gergoviae
Kuan-Jen Chen1, Ko-Jen Yang2, Chi-Chin Sun2,1
1Department of Ophthalmology, Linkou Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kweishan, Taoyuan, Taiwan, ROC.
This case study details a rare polymicrobial traumatic endophthalmitis caused by two specific bacteria. Successful treatment involved surgery and antibiotics, resulting in improved vision.
Area of Science:
- Ophthalmology
- Microbiology
Background:
- Traumatic endophthalmitis is a severe intraocular infection following eye trauma.
- Polymicrobial infections, though less common, present unique diagnostic and therapeutic challenges.
Observation:
- A rare case of polymicrobial traumatic endophthalmitis was observed.
- The causative agents identified were Enterococcus raffinosus and Enterobacter gergoviae.
Findings:
- Complete pars plana vitrectomy was performed as a surgical intervention.
- Intravitreal injections of vancomycin and amikacin were administered.
- The patient achieved a final visual acuity of 20/200.
Implications:
- This case highlights the importance of prompt and aggressive management for polymicrobial endophthalmitis.
- Successful visual outcomes are achievable with appropriate surgical and antimicrobial strategies.
- Understanding the specific pathogens is crucial for targeted antibiotic therapy in traumatic endophthalmitis.
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