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Updated: Jun 25, 2026

Lumican Extraction from Amniotic Membrane and Determination of its Storage Temperature
04:21

Lumican Extraction from Amniotic Membrane and Determination of its Storage Temperature

Published on: October 14, 2022

[Topical amniotic fluid: a potential new alternative for ocular surface diseases]

Guilherme Goulart Quinto1, Suy Anne Rebouças Martins, Renata Tiemi

  • 1Wilmer Ophthalmological Institute, The Johns Hopkins University School of Medicine - Baltimore, MD 21287-0005, USA.

Arquivos Brasileiros De Oftalmologia
|March 11, 2009
PubMed

Amniotic fluid bathes the fetus during intrauterine life and is in permanent contact with the fetal ocular surface in this important period of development. It contains a series of growth factors that may have multiple effects on the wound healing process. These factors are thought to accelerate the recovery of corneal sensitivity and nerve regeneration after keratorefractive procedures, and also may control scar formation and balance the ocular surface after topical application. Hundreds of different proteins have been identified in the human amniotic fluid, and the role of each still not quite understood. The outcomes obtained so far with amniotic fluid application to ocular surface diseases suggest a promising therapy. Research is underway to identify the effects of specific factors of the amniotic fluid in ocular inflammation. The purpose of this review is to report the properties and current utilizations of amniotic fluid as well as to summarize the recent studies related to the use of this fluid for ocular surface diseases.

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