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Updated: Jun 25, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Performance of patients with refractory obsessive-compulsive disorder in the Frontal Systems Behavior Scale
Marcelo Camargo Batistuzzo1, Anita Taub, Eduardo Nakano
1Department & Institute of Psychiatry, Clinical Hospital, University of Sao Paulo Medical School (FMUSP), Sao Paulo-SP, Brazil. marcelobatistuzzo@gmail.com
Objective:
To compare the performance of patients with obsessive-compulsive disorder (OCD) refractory to conventional treatments to healthy controls according to the Frontal Systems Behaviour Scale (FrSBe), comparing the scale scores within each group (Self or Family) and correlating FrSBe with Y-BOCS, DY-BOCS, tic disorder and age of first symptoms.
Method:
Twenty OCD patients and 20 healthy controls were assessed using the FrSBe, a scale designed to evaluate frontal syndromes.
Results:
The patients had higher scores when compared with the control group (p value < .001) in terms of total score on the scale for both profile forms (Self and Family). In addition, there was a significant difference between the scores reported by the patients and their respective relatives. However, no correlation was observed between the scale and the other variables.
Conclusions:
The scale was able to clearly differentiate patients with OCD from healthy controls. This finding suggests that the FrSBe can be used not only in neurologic patients but also in psychiatric cases such as refractory OCD.
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