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Related Concept Videos

Zygotic Development And Stem Cell Formation01:10

Zygotic Development And Stem Cell Formation

The development of all multicellular organisms starts with the fusion of haploid cells called sperm and egg to form a diploid zygote. A zygote is a totipotent cell that can develop into a complete organism. The zygote undergoes cell division or cleavage to form an 8-cell mass. Until this stage, the cells are spherical, loosely attached, and remain totipotent. Totipotent cells are capable of developing both the embryonic and the extraembryonic tissues. However, as they continue to divide, they...
Multipotency of Hematopoietic Stem Cells01:19

Multipotency of Hematopoietic Stem Cells

The hematopoietic stem cells or HSCs are multipotent, meaning they can differentiate and give rise to all blood and immune cells. HSCs are maintained in the quiescent stage until an external stimulus initiates their differentiation. The multipotent HSCs exist as two heterogeneous populations, long-term repopulating cells (LTRC) and short-term repopulating cells (STRC). The two HSC populations have different surface markers or receptors and are classified based on quiescence and long-term...
Multipotency and Niche of Bulge Stem Cell01:06

Multipotency and Niche of Bulge Stem Cell

A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
Hematopoiesis01:21

Hematopoiesis

The process of blood cell formation is called hematopoiesis. Hematopoiesis starts early during development, on the seventh day of embryogenesis. This phase of hematopoiesis is called the primitive wave, wherein the extraembryonic yolk sac allows the production of erythroid cells and endothelial cells from a common precursor called hemangioblast. The erythroid cells provide oxygen to support the growth of the rapidly dividing embryo. Hemangioblasts later develop into hematopoietic stem cells or...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Production of Formed Elements01:34

Production of Formed Elements

Hemangioblasts are multipotent stem cells originating from the mesoderm. They give rise to hematopoietic stem cells (HSCs), which undergo hematopoiesis to produce all the formed elements of blood. This process is regulated by a complex network of hematopoietic growth factors, including transcription factors, growth factors, and cytokines. These factors stimulate the HSCs to divide and differentiate, though some HSCs remain undifferentiated to maintain a self-renewing pool.
Most HSCs commit to...

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Related Experiment Video

Updated: Jun 25, 2026

Generation of Transgenic Hydra by Embryo Microinjection
09:10

Generation of Transgenic Hydra by Embryo Microinjection

Published on: September 11, 2014

Hydra and the evolution of stem cells.

Thomas C G Bosch1

  • 1Zoological Institute, Christian-Albrechts-University Kiel, Kiel, Germany. tbosch@zoologie.uni-kiel.de

Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology
|March 11, 2009
PubMed
Summary

Hydra possess remarkable immortality due to asexual reproduction, relying on continuously self-renewing stem cells. Studying these stem cells offers vital insights into fundamental biology, including aging and reprogramming.

Area of Science:

  • * Developmental Biology
  • * Stem Cell Biology
  • * Evolutionary Biology

Background:

  • * Hydra exhibit biological immortality, largely attributed to their capacity for asexual reproduction via budding.
  • * This process necessitates a population of stem cells with continuous self-renewal capabilities.
  • * Recent advancements in technology and genomics allow for in vivo analysis of these unique stem cells.

Purpose of the Study:

  • * To review the historical research on Hydra stem cells.
  • * To explore the potential of current technologies in studying these cells.
  • * To provide insights into stem cell biology, senescence, reprogramming, and evolutionary origins.

Main Methods:

  • * Review of existing literature on Hydra stem cell research.

More Related Videos

Generation and Long-term Maintenance of Nerve-free Hydra
06:33

Generation and Long-term Maintenance of Nerve-free Hydra

Published on: July 7, 2017

Related Experiment Videos

Last Updated: Jun 25, 2026

Generation of Transgenic Hydra by Embryo Microinjection
09:10

Generation of Transgenic Hydra by Embryo Microinjection

Published on: September 11, 2014

Generation and Long-term Maintenance of Nerve-free Hydra
06:33

Generation and Long-term Maintenance of Nerve-free Hydra

Published on: July 7, 2017

  • * Analysis of novel technologies and genomic resources for in vivo studies.
  • * Examination of conserved signaling pathways governing stem cell differentiation.
  • Main Results:

    • * Hydra stem cells are crucial for asexual reproduction and immortality.
    • * Conserved signaling pathways regulate stem cell differentiation in Hydra.
    • * In vivo analysis is becoming increasingly feasible with new technologies.

    Conclusions:

    • * Studying Hydra stem cells provides critical insights into fundamental biological processes.
    • * Research promises to advance understanding of cellular senescence, lineage programming, and tissue homeostasis.
    • * Hydra serve as a powerful model for investigating the evolutionary origins of stem cells.