Expanded newborn screening in Oklahoma

Oklahoma is currently in the process of implementing tandem mass spectrometry (MS/MS) as a part of its newborn screening program. This technology will vastly expand the number of newborn disorders for which Oklahoma can screen. This article briefly reviews the history of newborn screening and discusses the current technology involved with this process. It also addresses old and new controversies associated with newborn screening and its expansion. Finally, it touches on some future directions in newborn screening.