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Development of anti-hGH antibodies during therapy with authentic human growth hormone
K Lundin1, L Berger, F Blomberg
1Kabi Pharmacia Peptide Hormones, Stockholm, Sweden.
Acta Paediatrica Scandinavica. Supplement
|January 1, 1991
Children treated with authentic human growth hormone (Genotropin) in clinical trials between 1985 and 1989 were tested for the presence of anti-hGH antibodies. The incidence of antibodies after 12 months of treatment was 4/373 (1.1%). Mean binding capacity was 0.07 mg/l. The results suggest that Genotropin has low immunogenicity.
Children treated with authentic human growth hormone (Genotropin) in clinical trials between 1985 and 1989 were tested for the presence of anti-hGH antibodies. The incidence of antibodies after 12 months of treatment was 4/373 (1.1%). Mean binding capacity was 0.07 mg/l. The results suggest that Genotropin has low immunogenicity.