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Related Concept Videos

Improving Translational Accuracy02:07

Improving Translational Accuracy

Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
Improving Translational Accuracy02:07

Improving Translational Accuracy

Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Translation01:31

Translation

Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Proteins are called the...

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Related Experiment Video

Updated: Jun 25, 2026

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications
09:20

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications

Published on: February 23, 2019

Translating medical terminologies through word alignment in parallel text corpora.

Louise Deléger1, Magnus Merkel, Pierre Zweigenbaum

  • 1INSERM, UMR_S 872, Eq. 20, Centre des cordeliers, Paris F-75006, France. louise.deleger@spim.jussieu.fr

Journal of Biomedical Informatics
|March 12, 2009
PubMed
Summary

This study introduces an automated method for medical terminology translation using parallel text corpora. The approach successfully generated accurate new translations, improving the efficiency of multilingual terminology development.

Related Experiment Videos

Last Updated: Jun 25, 2026

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications
09:20

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications

Published on: February 23, 2019

Area of Science:

  • Medical Informatics
  • Computational Linguistics
  • Natural Language Processing

Background:

  • Developing international medical terminologies is complex and time-consuming.
  • Existing methods for terminology translation can be inefficient.
  • The need for accurate and efficient multilingual medical resources is growing.

Purpose of the Study:

  • To present a methodology for automatically acquiring new medical term translations.
  • To test the methodology on English-French parallel text corpora.
  • To evaluate the quality and utility of the automatically generated translations.

Main Methods:

  • Collected a parallel English-French corpus.
  • Employed word alignment techniques to detect translations of medical terms.
  • Tested the method on terms from MeSH, SNOMED CT, and MedlinePlus Health Topics.
  • Conducted expert review for a subset of generated translations.

Main Results:

  • Achieved high percentages of linguistically correct new translations: 74.8% for MeSH, 77.8% for SNOMED CT, and 76.3% for MedlinePlus.
  • Expert review confirmed 61.5% of MeSH translations as desirable additions to the French MeSH.
  • Demonstrated the effectiveness of word alignment in parallel corpora for terminology translation.

Conclusions:

  • The proposed methodology successfully generates good-quality new translations for medical terminologies.
  • Word alignment in text corpora is a suitable approach to aid in terminology translation.
  • The method offers a flexible framework applicable to various European languages and processing tools.