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Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Cyanoacrylate glue for type iii lad perforation
1Department of Cardiology, GB Pant Hospital, JLN Marg, New Delhi.
Indian Heart Journal
|March 12, 2009
Summary
Coronary artery perforation, a rare complication of percutaneous coronary intervention, can be serious. This case demonstrates successful management of severe left anterior descending artery perforation using cyanoacrylate glue.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Device Technology
Background:
- Percutaneous coronary intervention (PCI) is a common procedure for treating coronary artery disease.
- Coronary artery perforation (CAP) is a rare but serious complication of PCI.
- Type III CAP, involving the artery wall and surrounding structures, often requires emergency surgery.
Observation:
- A patient experienced a type III perforation of the left anterior descending artery during PCI.
- Initial attempts to achieve hemostasis were unsuccessful, posing a risk of emergency surgery.
- The perforation was successfully sealed using cyanoacrylate glue.
Findings:
- Cyanoacrylate glue provided effective hemostasis for a complex type III coronary artery perforation.
- This interventional technique avoided the need for emergency open-heart surgery.
- The patient experienced a favorable outcome following the minimally invasive treatment.
Implications:
- Cyanoacrylate glue represents a viable alternative treatment for specific types of coronary artery perforation.
- This approach may reduce the need for emergent surgical intervention in complex PCI cases.
- Further research into endovascular sealing techniques for PCI complications is warranted.

