Early and late outcomes of coil embolization of pulmonary sequestration in children
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Published on: November 4, 2021
Kuang-Jen Chien1, Ta-Cheng Huang, Chu-Chuan Lin
1Department of Pediatrics, Kaohsiung Veterans General Hospital, National Yang-Ming University, Kaohsiung, Taiwan.
Insights
Coil embolization is a safe and effective treatment for pediatric pulmonary sequestration (PS), offering good long-term outcomes. This minimally invasive approach avoids surgical resection for this congenital lung malformation.
Area of Science:
- Interventional Radiology
- Pediatric Surgery
- Pulmonology
Background:
- Pulmonary sequestration (PS) involves non-functioning lung tissue supplied by aberrant systemic arteries.
- Surgical resection is the traditional treatment, but less invasive options are being explored.
- Previous case reports suggest coil embolization is feasible for PS.
Purpose of the Study:
- To evaluate the early and long-term outcomes of coil embolization for pediatric PS.
- To identify risk factors for major adverse cardiovascular and pulmonary events associated with this procedure.
Main Methods:
- Coil embolization of the feeding systemic artery was performed in 6 pediatric patients with PS.
- Patients were followed for early and late complications.
- Computed tomography was used to assess residual systemic flow.
Main Results:
- Four out of six patients were considered cured after the initial procedure.
- Two patients required a second embolization due to residual systemic flow.
- One patient experienced transient ischemic changes in the lower limb; no other late complications or recurrent pneumonia were observed.
Conclusions:
- Coil embolization is a safe and feasible treatment for pediatric pulmonary sequestration.
- The procedure demonstrates good long-term outcomes.
- It presents a viable alternative to surgical resection.
Background:
Pulmonary sequestration (PS) is characterized by non-functioning lung tissue fed from 1 or several aberrant systemic arteries. The classical therapeutic approach is surgical resection. Several case reports have shown that coil embolization is feasible, but this technique has not been evaluated in a larger series of consecutively treated patients. The purpose of our study was to assess the early and long-term outcomes of coil embolization of PS in children and to determine the risk factors of early and late major adverse cardiovascular and pulmonary events.
Methods And Results:
Between March 1999 and December 2004, 6 patients (2 boys, 4 girls, mean age 4.7 +/-3.8 years) with PS were treated by coil embolization of the feeding systemic artery. Four patients were considered to have been cured and 2 patients required a second coil embolization 6 months later because of residual systemic flow seen on computed tomography. Transient ischemic change of the lower limb occurred in the youngest patient. None of the other patients had any late complications or recurrent pneumonia.
Conclusions:
Coil embolization of PS is safe and feasible, with a good late outcome.
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