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Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
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Memory complaints and memory performance in the menopausal transition.

Miriam Weber1, Mark Mapstone

  • 1From the Departments of 1Physical Medicine and Rehabilitation and 2Neurology, The University of Rochester Medical Center, Rochester, NY 14642, USA. miriam_weber@urmc.rochester.edu

Menopause (New York, N.Y.)
|March 12, 2009
PubMed
Summary

Perimenopausal women’s memory complaints are linked to poorer memory encoding and depression, not just subjective feelings. Estrogen levels also impact encoding performance, suggesting a complex interplay of factors.

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Area of Science:

  • Neuroscience
  • Endocrinology
  • Psychology

Background:

  • Perimenopausal memory complaints are common but poorly understood.
  • The relationship between subjective memory issues and objective cognitive performance requires further investigation.

Purpose of the Study:

  • To examine the link between perimenopausal memory complaints and objective neuropsychological test performance.
  • To explore the influence of hormone levels, mood, and sleep on memory function during perimenopause.

Main Methods:

  • Twenty-four perimenopausal women completed cognitive tests and questionnaires on mood, menopausal symptoms, and subjective memory.
  • Serum estradiol and follicle-stimulating hormone levels were measured.

Main Results:

  • No association was found between memory complaints and retentive memory performance.
  • Memory complaints correlated with poorer memory encoding and increased depressive symptoms.
  • Depressive symptoms and estrogen levels predicted encoding performance.

Conclusions:

  • Perimenopausal memory complaints are complex, involving mood, memory, and hormonal factors.
  • Some women may be more susceptible to subjective memory issues and attention-related cognitive decline.