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Infant Auditory Processing and Event-related Brain Oscillations
Published on: July 1, 2015
Modeling the developmental patterns of auditory evoked magnetic fields in children
Rupesh Kotecha1, Maria Pardos, Yingying Wang
1MEG Center, Department of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.
Plos One
|March 12, 2009
Summary
Magnetoencephalography (MEG) reveals distinct auditory response patterns in children, with M70 latency correlating with age and serving as an index for auditory development. These findings highlight crucial developmental changes in the brain's auditory cortex.
Area of Science:
- Neuroscience
- Developmental Biology
- Auditory Neuroscience
Background:
- Magnetoencephalography (MEG) is increasingly vital for assessing pediatric brain disorders.
- Understanding functional brain development in children is crucial.
Purpose of the Study:
- To characterize developmental patterns of auditory evoked magnetic responses.
- To investigate the influence of age and gender on these responses.
Main Methods:
- Studied 60 children and 20 adults using a 275-channel MEG system.
- Analyzed auditory evoked magnetic responses (M50, M70, M100).
Main Results:
- Identified M50, M70, and M100 responses in children.
- M70 and M100 latencies decreased with age; M50 latency decreased in the right hemisphere.
- Right hemisphere responses showed faster latency shortening, with M70 latency strongly correlating with age.
- M70 amplitudes peaked at 12-14 years and decreased thereafter.
- Source estimates differed between children and adults for M50 and M70.
- Gender influenced developmental patterns.
Conclusions:
- Established clear developmental patterns in the auditory cortex.
- M70 latency in the right hemisphere is a proposed index of auditory development (equation provided).
- Emphasized the significance of M50 and M70 in the developing brain.
