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Intracranial clear-cell meningioma

Lu Ma1, Wen-Ke Liu, Kun Wang

  • 1Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, PR China.

Acta Neurochirurgica
|March 12, 2009
PubMed

Insights

Intracranial clear-cell meningioma (CCM) is rare and often misdiagnosed. This study details a pediatric case and reviews 35 intracranial CCMs, highlighting their unique features.

Area of Science:

  • Neuro-oncology
  • Pediatric Neurosurgery
  • Pathology

Background:

  • Intracranial clear-cell meningioma (CCM) is a rare subtype of meningioma.
  • CCMs are more commonly found in the spine than the brain.
  • Distinguishing CCMs from other meningioma subtypes is crucial for accurate diagnosis.

Observation:

  • A case of occipital parietal CCM in a 6-year-old child is presented.
  • A comprehensive review of 35 reported intracranial CCM cases from 1995 to the present was conducted.
  • Clinical, radiological, and histopathological data were analyzed.

Findings:

  • Intracranial CCMs exhibit distinct characteristics that differentiate them from other meningioma subtypes.
  • The review provides insights into the typical presentation and features of pediatric and adult intracranial CCMs.
  • Histopathological analysis is key to confirming the diagnosis of CCM.

Implications:

  • This review enhances understanding of rare intracranial clear-cell meningiomas.
  • Improved diagnostic criteria can lead to better patient management and outcomes.
  • Further research into CCM pathogenesis and treatment is warranted.

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