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Published on: August 12, 2020
Neonatal hyperbilirubinemia and early discharge from the maternity ward
Daniele De Luca1, Virgilio P Carnielli, Piermichele Paolillo
1Division of Neonatology, Casilino General Hospital, ASL RM-B, Rome, Italy. dm.deluca@fastwebnet.it
Insights
Early hospital discharge for newborns can complicate jaundice management. However, reliable prediction tools and planned follow-up enable safe early discharge, preventing newborn rehospitalization due to hyperbilirubinemia.
Area of Science:
- Neonatal Medicine
- Pediatrics
- Public Health
Background:
- Early discharge from maternity hospitals is increasingly common.
- Hyperbilirubinemia (jaundice) is a frequent cause of newborn rehospitalization.
- Current practices may pose challenges for effective jaundice management in early-discharged infants.
Purpose of the Study:
- To review guidelines for jaundice management and early discharge.
- To provide an evidence-based update on predictive tools for neonatal jaundice.
- To offer practical advice for safe early discharge and follow-up protocols.
Main Methods:
- Review of existing guidelines for neonatal jaundice and early discharge.
- Analysis of evidence on predictive factors for hyperbilirubinemia.
- Development of a practical flowchart for jaundice risk assessment and management.
Main Results:
- Gestational age, nomogram evaluation, two-point bilirubin assay, and rate of rise are key predictors.
- Identifying the appropriate bilirubin nomogram curve is crucial.
- Unforeseen risk factors for jaundice require careful consideration.
- Predictive tools can reliably forecast jaundice risk.
Conclusions:
- Available predictive tools enable reliable jaundice prediction.
- Safe early discharge is achievable with adequate, prediction-based follow-up.
- Implementing evidence-based protocols can mitigate risks associated with early discharge and jaundice.
Abstract:
Early discharge from the maternity hospital is almost becoming the rule: it is not clear if this practice actually increases the rate of newborn rehospitalization, but it surely poses some problems for jaundice management, since hyperbilirubinemia is the most frequent reason for hospital readmission. Available guidelines for jaundice management and early discharge are reviewed. Evidence-based update is given about four new points: use of gestational age as predictor jointly with the nomogram evaluation, two-point bilirubin assay, and rate of rise evaluation; choice of the "right" curve and unforeseen jaundice risk factors. In conclusion, available predictive tools allow reliable jaundice prediction and safe early discharge if adequate follow-up is planned according to the prediction. Advice about things to avoid is provided together with a practical flowchart based on guidelines and recent evidence-based data.
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