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Related Concept Videos

Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...

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Related Experiment Video

Updated: Jun 24, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

[Kidney injuries].

J Pfitzenmaier1, S Buse, A Haferkamp

  • 1Urologische Universitätsklinik, Heidelberg, Germany. Jesco.Pfitzenmaier@med.uni-heidelberg.de

Der Unfallchirurg
|March 12, 2009
PubMed
Summary
This summary is machine-generated.

Conservative management is now favored for blunt renal trauma, even for severe injuries. Most cases of urinary extravasation resolve without intervention, and a multimodal approach including interventional radiology is increasingly common.

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A Quantitative Detection Method for MicroRNAs in the Kidney of an Ischemic Kidney Injury Mouse Model
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Last Updated: Jun 24, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
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Published on: February 2, 2021

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A Quantitative Detection Method for MicroRNAs in the Kidney of an Ischemic Kidney Injury Mouse Model

Published on: September 11, 2020

Area of Science:

  • Urology
  • Trauma Surgery
  • Interventional Radiology

Background:

  • Blunt trauma is the leading cause of kidney injuries in industrialized nations.
  • Management strategies for renal trauma remain a subject of debate.
  • Historically, surgical intervention was common, but conservative approaches are gaining favor.

Purpose of the Study:

  • To review current trends in the management of blunt renal trauma.
  • To highlight the increasing role of conservative treatment and interventional radiology.
  • To discuss the efficacy and outcomes of various management strategies.

Main Methods:

  • Review of current literature and clinical practices regarding renal trauma management.
  • Analysis of conservative versus interventional approaches for different injury grades.
  • Evaluation of the success rates of angioembolization and the necessity of urinary diversion.

Main Results:

  • Conservative management is increasingly preferred, even for high-grade renal trauma (Grade IV/V).
  • Urinary diversion via nephrostomy or ureteral stenting is often unnecessary, with 90% of extravasation resolving spontaneously.
  • Angioembolization demonstrates a 70-80% success rate in managing renal trauma.
  • A multimodal approach involving interventional radiologists is becoming standard for severe injuries.

Conclusions:

  • Modern management of blunt renal trauma leans towards conservative strategies.
  • Interventional radiology plays a crucial role in the multimodal treatment of high-grade renal injuries.
  • While effective, angioembolization carries potential long-term risks such as hypertension and reduced kidney function.