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Related Concept Videos

Gas Chromatography: Introduction01:13

Gas Chromatography: Introduction

Gas chromatography (GC) is a technique for separating and analyzing volatile compounds in a sample. Its primary purpose is to identify and quantify components in complex mixtures, making it essential in fields such as environmental analysis, pharmaceuticals, and petrochemicals. GC is also called vapor-phase chromatography (VPC) or gas-liquid partition chromatography (GLPC).
In GC,  a sample is vaporized and mixed with an inert carrier gas (the mobile phase), which transports it through a column.
Gas Chromatography–Mass Spectrometry (GC–MS)01:14

Gas Chromatography–Mass Spectrometry (GC–MS)

Gas chromatography–mass spectrometry (GC–MS) is the combination of analytical techniques of gas chromatography and mass spectrometry in a single instrument for analyzing a mixture of compounds. The gas chromatograph separates the compounds in the mixture, and the mass spectrometer analyzes each compound separately to determine the molecular masses and molecular structures.
A gas chromatograph consists of a long, narrow capillary column with a polysiloxane coating on the inner wall. The coating...
Gas Chromatography: Overview of Detectors01:13

Gas Chromatography: Overview of Detectors

Detectors in gas chromatography (GC) help identify and quantify the components of a mixture by translating chemical properties into measurable signals, which are displayed on a chromatogram. Detectors can be categorized into two main types: destructive and non-destructive.
A non-destructive detector allows a sample to be analyzed without altering or consuming it, meaning the sample can be collected after detection for further analysis. Examples include thermal conductivity detectors and...
Gas Chromatography: Types of Columns and Stationary Phases01:17

Gas Chromatography: Types of Columns and Stationary Phases

Gas chromatography (GC) relies on stationary phases to separate and analyze components in a sample. There are two main types of stationary phases: liquid and solid. Liquid stationary phases are non-volatile, thermally stable, and chemically inert liquids coated onto the column. Solid stationary phases are particles of adsorbent material, such as silica gel or molecular sieves.
For an analyte to remain on the column for a sufficient amount of time, it must exhibit some level of compatibility (or...
Gas Chromatography: Types of Detectors-II01:19

Gas Chromatography: Types of Detectors-II

In gas chromatography, different detectors are employed to meet specific analytical needs. These detectors are often categorized based on their detection mechanisms and the types of compounds they are best suited to analyze. Thermal Conductivity Detectors (TCD), Flame Ionization Detectors (FID), and Electron Capture Detectors (ECD) represent common categories, each with unique operating principles and applications. However, beyond these, several other detectors are designed for more specialized...
Gas Chromatography: Sample Injection Systems01:08

Gas Chromatography: Sample Injection Systems

In gas chromatography, the sample is introduced as a vapor plug into the carrier gas stream for high efficiency and resolution. A microsyringe injects the sample solution into a heated sample port, vaporizing it and mixing it with the carrier gas. This process is important to ensure the sample is properly prepared for analysis. Thermally sensitive samples can be injected directly into the column and volatilized by slowly increasing the column temperature.
Two primary injection methods are used...

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Chromatographic Fingerprinting by Template Matching for Data Collected by Comprehensive Two-Dimensional Gas Chromatography
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Chromatographic Fingerprinting by Template Matching for Data Collected by Comprehensive Two-Dimensional Gas Chromatography

Published on: September 2, 2020

Comprehensive two dimensional gas chromatography review.

Hernan J Cortes1, Bill Winniford, Jim Luong

  • 1The Dow Chemical Company, Analytical Sciences, Midland, MI 48667, USA. hjcortes1@gmail.com

Journal of Separation Science
|March 12, 2009
PubMed
Summary
This summary is machine-generated.

This review covers advances in 2-D comprehensive gas chromatography (GC x GC) from 2007-2008, focusing on modulation, data handling, and relevant applications. It also includes industrial perspectives and future development suggestions.

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Area of Science:

  • Analytical Chemistry
  • Chromatography

Background:

  • 2-D comprehensive gas chromatography (GC x GC) is an advanced separation technique.
  • Continuous development is crucial for its effective application.

Purpose of the Study:

  • To review advances, developments, and applications in GC x GC.
  • To emphasize modulation, data handling, and current applications.
  • To summarize industrial perspectives and suggest future developments.

Main Methods:

  • Literature review of GC x GC advancements from 2007 to October 2008.
  • Focus on modulation techniques and data processing methods.
  • Analysis of current and relevant applications.

Main Results:

  • Significant progress in GC x GC modulation and data handling techniques.
  • Diverse applications demonstrating the technique's utility.
  • Identification of areas for future research and industrial implementation.

Conclusions:

  • GC x GC technology has seen notable advancements.
  • Further development in modulation and data analysis is beneficial.
  • Industrial adoption and application continue to grow.