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The effect of anti-sensitivity dentifrices on brushing abrasion of eroded dentin in vitro
Nathan Hughes1, Stephen Mason, Jonathan Creeth
1GlaxoSmithKline Consumer Healthcare, Weybridge, Surrey, UK. nathan.l.hughes@gsk.com
Objective:
To investigate the abrasive effects of three marketed anti-sensitivity, and one marketed regular dentifrice on dentin, using an erosion-abrasion in vitro model.
Methods:
Standardized human dentin specimens were prepared and exposed to cycles of erosion, remineralization, and tooth brushing, utilizing the four commercially available dentifrices. Dentin surface loss was then measured by optical profilometry after a total of nine complete cycles. The RDA and pH values of the dentifrices were also measured to assist in the interpretation of results.
Results:
Profilometry showed significantly greater dentin surface loss for both Colgate Sensitive Fresh Stripe and Colgate Sensitive Multi Protection when compared with Sensodyne Total Protection or Crest Cavity Protection dentifrices. The abrasive level of dentifrices correlated positively (r-squared = 0.66; p < 0.05) with dentin surface loss.
Conclusion:
This study demonstrated that the abrasivity of dentifrices can have a significant effect on the wear of eroded dentin in vitro.
