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Updated: Jun 24, 2026

Modeling Cataract Surgery in Mice
Published on: December 1, 2023
Adverse medical events associated with cataract surgery performed under topical anaesthesia
Phillipa L Sharwood1, David Thomas, Timothy V Roberts
1Northern Clinical School, University of Sydney, Royal North Shore Hospital, New South Wales, Australia.
Background:
Cataract surgery in Australia is increasingly performed in an elderly population with multiple medical comorbidities. The purpose of this study was to investigate the frequency and type of adverse medical events associated with cataract surgery performed under topical anaesthesia with light sedation.
Methods:
Retrospective analysis was undertaken for 631 consecutive cases of clear corneal phaco-emulsification and implant surgery performed under assisted topical anaesthesia, by a single surgeon (TR) in a private ophthalmic day surgery unit. In the 238 patients who underwent bilateral surgery, data from the first procedure for each patient were analysed, unless the second procedure was associated with greater morbidity.
Results:
A total of 393 procedures were included in the study. The mean age was 73 +/- 11 years with 75% of patients having at least one significant medical comorbidity. The most common comorbidities were hypertension (51%), gastro-oesophageal reflux (19%), angina and myocardial infarction (14%), diabetes (13%) and asthma (9%). Significant intraoperative adverse medical events requiring intervention occurred in four cases (1%): bradycardia occurred in three cases and hypotension in one case. None of these adverse events resulted in death or hospitalization. There were no postoperative adverse events, hospitalizations or deaths within 7 days. Minor changes in heart rate, blood pressure and oximetry not requiring intervention were observed in 35 cases (9%).
Conclusion:
This retrospective analysis shows that cataract surgery performed under assisted topical anaesthesia is safe with a low rate of systemic complications despite being performed in an elderly population.
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