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Conjunctival and episcleral Splendore-Hoeppli phenomenon
Nigel Pinto1, Lawrence Hirst, Michael Whitby
1Princess Alexandra Hospital, Brisbane, Queensland, Australia. nigelpinto@y7mail.com
Clinical & Experimental Ophthalmology
|March 13, 2009
Summary
The rare Splendore-Hoeppli phenomenon, a pathological state of unknown cause, was observed in both eyes of a patient. This condition spontaneously resolved within 10 weeks, even during steroid withdrawal, suggesting it
Area of Science:
- Ophthalmology
- Pathology
Background:
- The Splendore-Hoeppli phenomenon is a rare pathological condition with an unknown etiology.
- First described in 1908, its underlying mechanisms remain poorly understood.
Observation:
- A case of bilateral Splendore-Hoeppli phenomenon in a 36-year-old woman is reported.
- The ocular lesions developed despite the patient receiving high-dose oral steroids.
Findings:
- The Splendore-Hoeppli phenomenon resolved spontaneously within a 10-week period.
- Lesion resolution occurred even after the cessation of steroid therapy.
Implications:
- The spontaneous resolution challenges the hypothesis of an autoimmune response as the primary cause.
- Further research is needed to elucidate the etiology of the Splendore-Hoeppli phenomenon.
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