Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypertension in the elderly patient.

C Ryan1

  • 1San Francisco Heart Institute, Daly City, CA 94015.

American Heart Journal
|October 1, 1991
PubMed
Summary

Treating hypertension in elderly individuals significantly lowers cardiovascular disease and stroke risks. Ongoing trials like SHEP and STH aim to further clarify treatment benefits for isolated systolic hypertension in older adults.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The utility of <i>T. pallidum</i> PCR testing in the diagnosis of congenital syphilis: a systematic review.

Infectious diseases (London, England)·2025
Same author

Central Blood Pressure and Augmentation Index in Older Adults With Intellectual Disabilities.

Journal of intellectual disability research : JIDR·2025
Same author

Pharmacist prescribing in cancer services: A scoping review.

Research in social & administrative pharmacy : RSAP·2025
Same author

Sex-related pathophysiological mechanisms may be present before symptoms of HFpEF develop.

ESC heart failure·2025
Same author

Comparing self-report medication data from a longitudinal study on intellectual disability and national dispensing records.

Journal of intellectual disability research : JIDR·2024
Same author

Echocardiography in Training in Intensive Care - What Have We Learned.

Irish medical journal·2024

Area of Science:

  • Gerontology
  • Cardiovascular Medicine
  • Clinical Trials

Background:

  • Elderly individuals with hypertension face increased risks of cardiovascular disease and stroke.
  • Diastolic hypertension treatment in the elderly shows reduced cardiovascular morbidity.
  • Isolated systolic hypertension in older adults is strongly linked to stroke and cardiovascular mortality.

Purpose of the Study:

  • To review the impact of hypertension treatment on cardiovascular and cerebrovascular outcomes in the elderly.
  • To highlight the unique mechanisms of hypertension in older populations, such as peripheral vascular resistance.
  • To discuss ongoing research, including the Systolic Hypertension European trial and the Systolic Hypertension in the Elderly Patient trial.

Main Methods:

  • Review of existing clinical trial data on hypertension treatment in elderly patients.
  • Analysis of the relationship between isolated systolic hypertension and adverse cardiovascular and cerebrovascular events.
  • Discussion of the physiological mechanisms underlying hypertension in the elderly.

Main Results:

  • Treatment of diastolic hypertension in the elderly reduces cardiovascular morbidity.
  • Treatment in the Systolic Hypertension in the Elderly Patient pilot trial reduced stroke morbidity and mortality.
  • Isolated systolic hypertension presents a significant risk for stroke and cardiovascular disease in older adults.

Conclusions:

  • Hypertension management is crucial for reducing morbidity and mortality in elderly patients.
  • Further research from ongoing trials is needed to fully understand the treatment of isolated systolic hypertension in this population.
  • Peripheral vascular resistance is a key factor in elderly hypertension, and exercise may help reduce it.

Related Experiment Videos