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Updated: Jun 24, 2026

Orthotopic Hind Limb Transplantation in the Mouse
Published on: February 12, 2016
Free tissue transfers in the first 2 years of life--a successful cost effective and humane option
R M Pinder1, A Hart, R I S Winterton
1The Department of Plastic Surgery, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK. rich.pinder@doctors.org.uk
Insights
Free tissue transfer (FTT) is a safe and effective reconstructive surgery for young children under two years old. This microsurgical technique offers successful outcomes, retaining growth potential and reducing patient and family distress.
Area of Science:
- Microsurgery
- Pediatric Surgery
- Plastic Surgery
Background:
- Young children are favorable candidates for microsurgical reconstruction due to fewer risk factors for flap failure.
- Free tissue transfer (FTT) in pediatric reconstructive surgery preserves growth potential and minimizes patient/family distress.
- FTT reduces the number and duration of care episodes in pediatric patients.
Purpose of the Study:
- To present a single center's 15-year experience with FTT in children under two years of age.
- To demonstrate the successful application of FTT in infants.
- To outline key aspects of patient selection, pre-operative counseling, and operative management for FTT in this age group.
Main Methods:
- Prospective data collection of all free flaps performed in children under two years old.
- Analysis of 47 flaps across 37 procedures in 32 patients.
- Review of indications including congenital defects, trauma, and meningococcal septicemia.
Main Results:
- A high flap survival rate of over 97% (46 out of 47 flaps).
- Comparable operative times, ischemia times, re-exploration, complication, and flap failure rates to adult or older pediatric series.
- No inherent infant-specific factors were found to preclude the use of FTT.
Conclusions:
- Free tissue transfer is a safe, humane, and cost-effective reconstructive option for children under two years old.
- Microsurgeons with appropriate facilities should not hesitate to perform FTT in very young children.
- The technique successfully addresses congenital defects, trauma, and post-septicemia reconstructions in infants.
Abstract:
Experience shows that young children are favourable candidates for microsurgical reconstruction, having few of the established risk factors for flap failure. In children's reconstructive surgery free tissue transfer (FTT) permits reconstruction whilst retaining growth potential, and reduces the overall number and duration of care episodes, and their related distress to the child and family. We present one centre's experience of free tissue transfer in children less than 2 years of age, over a 15-year period, demonstrating that free tissue transfer can be successfully employed in children under 2 years old. Salient aspects of patient selection, pre-operative counselling, and per-operative management are presented. Data from all free flaps in children under 2 years of age at the time of surgery were collected prospectively. Forty-seven flaps were performed as 37 separate procedures, in 32 children under 2 years of age. In ten patients, double transfers were performed in single procedures. Free tissue transfers were performed for reconstruction of congenital defects, following trauma and meningococcal septicaemia. All but one flap survived. In our series operative and ischaemia times, re-exploration, complication and flap failure rates were not higher than in comparable adult or older paediatric series from this unit, suggesting that there is no microvascular, or other, factor inherent to the infant that should preclude the use of free tissue transfer. Individual microsurgeons with appropriate facilities should not be inhibited from performing free tissue transfers which are humane and cost effective when compared with alternatives for very young children.
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