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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Cardiac and neuromuscular implications of left bundle branch block in left ventricular

C Stöllberger1, G Blazek, M Winkler-Dworak

  • 1Second Medical Department, Krankenanstalt Rudolfstiftung, Wein, Austria. claudia.stoellberger@chello.at

The Canadian Journal of Cardiology
|March 13, 2009
PubMed

Insights

Left bundle branch block (LBB) is common in left ventricular hypertrabeculation/noncompaction (LVHT). LBB is linked to older age, poorer heart function, and more extensive LVHT, but not NMDs or survival.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Cardiovascular Imaging

Background:

  • Left bundle branch block (LBB) is frequently observed in patients with left ventricular hypertrabeculation/noncompaction (LVHT).
  • Understanding the clinical implications of LBB in LVHT is crucial for patient management.

Purpose of the Study:

  • To compare LVHT patients with and without LBB.
  • To assess differences in LVHT characteristics, left ventricular function, symptoms, electrocardiographic findings, neuromuscular disorder (NMD) prevalence, and mortality.

Main Methods:

  • Retrospective analysis of echocardiographic data from 102 LVHT patients.
  • Comparison of clinical, functional, and electrocardiographic parameters between patients with and without LBB.

Main Results:

  • LBB patients were older and presented more frequently with exertional dyspnea and heart failure.
  • LBB was associated with reduced left ventricular systolic function and more extensive LVHT.
  • No significant difference in NMD prevalence or long-term survival was found between groups.

Conclusions:

  • LBB in LVHT is associated with increased age, impaired systolic function, and greater LVHT extension.
  • The prognostic significance of LBB in LVHT requires further investigation.
Abstract

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