Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prognostic indicators in compensated cirrhosis.

M Zoli1, M R Cordiani, G Marchesini

  • 1Istituti di Clinica Medica Generale e Terapia Medica, University of Bologna, Italy.

The American Journal of Gastroenterology
|October 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unravelling caramelization and Maillard reactions in glucose and glucose + leucine model cakes: Formation and degradation kinetics of volatile markers extracted during baking.

Food research international (Ottawa, Ont.)·2024
Same author

Unravelling caramelization and Maillard reactions in glucose and glucose + leucine model cakes: Formation and degradation kinetics of precursors, α-dicarbonyl intermediates and furanic compounds during baking.

Food chemistry·2021
Same author

Potential of model cakes to study reaction kinetics through the dynamic on-line extraction of volatile markers and TD-GC-MS analysis.

Food research international (Ottawa, Ont.)·2020
Same author

Kinetic study of furan and furfural generation during baking of cake models.

Food chemistry·2018
Same author

Twelve-month treatment with Liraglutide ameliorates Visceral Adiposity Index and common cardiovascular risk factors in type 2 diabetes outpatients.

Journal of endocrinological investigation·2014
Same author

Assessment of the first HPV vaccination campaign in two northern Italian health districts.

Vaccine·2011

Prognosis in compensated cirrhosis can be predicted using routine liver function tests and liver volume measurements. These factors, including albumin, bilirubin, and cholesterol, offer valuable insights for patient survival prediction.

Area of Science:

  • Hepatology
  • Internal Medicine
  • Clinical Prognostics

Background:

  • Compensated cirrhosis of the liver presents challenges in predicting patient prognosis.
  • Identifying reliable prognostic variables is crucial for clinical management.

Purpose of the Study:

  • To identify variables that predict survival in patients with compensated cirrhosis.
  • To evaluate the independent prognostic significance of routine laboratory tests and ultrasonographic measurements.

Main Methods:

  • Prospective follow-up of 100 patients with compensated cirrhosis (Child-Pugh class A and B) for a mean of 4.9 years.
  • Analysis of laboratory parameters, esophageal varices, ultrasonographic variables (liver volume, spleen volume, vessel calibers), and galactose elimination capacity.
  • Survival analysis using Cox's proportional hazards model.

Related Experiment Videos

Main Results:

  • Six parameters (albumin, bilirubin, liver volume, prothrombin activity, cholesterol, varices) initially predicted survival.
  • Step-wise Cox regression identified albumin, bilirubin, cholesterol, and liver volume as independent predictors of survival.
  • Galactose elimination capacity did not add significant prognostic value beyond routine tests.

Conclusions:

  • Routine liver function tests are effective in predicting survival in compensated cirrhosis.
  • Liver volume, measured by ultrasonography, is a significant and easily obtainable prognostic marker.
  • These findings support the integration of liver volume measurement into clinical practice for prognosis assessment.