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Updated: Jun 24, 2026
10:39
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Prochlorperazine--treatment for acute confusional migraine
Rakesh Khatri1, Andrew D Hershey, Brenda Wong
1University of Cincinnati-Department of Neurology, Cincinnati, OH, USA.
Headache
|March 13, 2009
Summary
Acute confusional migraine, a rare childhood disorder, has no standard treatment. Prochlorperazine showed variable success in resolving symptoms, with intravenous administration being highly effective in most cases.
Area of Science:
- Neurology
- Pediatrics
- Clinical Pharmacology
Background:
- Acute confusional migraine is a rare migraine variant predominantly affecting children.
- This condition lacks standardized diagnostic criteria and established acute symptomatic treatments.
Observation:
- Two pediatric patients experienced a total of six episodes of acute confusional migraine.
- Symptoms were observed to resolve following prochlorperazine administration.
Findings:
- Prochlorperazine demonstrated variable success in treating acute confusional migraine episodes.
- Intravenous prochlorperazine proved highly effective in resolving symptoms in 3 out of 4 treated episodes.
Implications:
- Prochlorperazine may represent a potential therapeutic option for acute confusional migraine.
- Further research is warranted to establish standardized treatment protocols for this rare migraine variant.
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