Related Experiment Video
Updated: Jun 24, 2026

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia
Published on: November 15, 2024
Very early hemorrhagic transformation of a subcortical infarction
Wei-Chieh Weng1, Wen-Yi Huang, Shan-Jin Ryu
1Department of Neurology, Kee-Lung Medical Center, Chang-Gung Memorial Hospital, Taiwan.
Abstract:
Hemorrhagic transformation (HT) of an ischemic stroke within 6 hours has never been documented. We reported a case of 65-year-old female experiencing sudden onset of slurred speech and right side weakness. Her past history disclosed rheumatic heart disease and atrial fibrillation. The National Institutes of Health stroke scale (NIHSS) score was 20. The brain computed tomography one hour after symptom onset revealed a faint hypodense lesion in the left striatum. The lesion, however, was transformed spontaneously into a large hematoma within 3 hours of symptom onset. This case thus developed a very early HT of a subcortical infarct of possible cardioembolic origin and high initial NIHSS score. Though rare, very early spontaneous HT does happen.
Related Concept Videos
Hemorrhagic Stroke ll: Pathophysiology
Hemorrhagic Stroke l: Introduction
Ischemic Stroke ll: Pathophysiology
Transient Ischemic Attack l: Introduction
Stroke: Introduction and Types
Ischemic Stroke l: Introduction

