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Essential Minerals for Bone Health

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...

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Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

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Published on: April 15, 2022

Next generation calcium phosphate-based biomaterials.

¹Paffenbarger Research Center, American Dental Association Foundation NIST, Gaithersburg, MD 20899, USA. laurence.chow@nist.gov

Dental Materials Journal

|March 14, 2009

Summary

This summary is machine-generated.

Calcium phosphate bone graft substitutes have been used for nearly 100 years. This review analyzes key properties of calcium phosphate cements to improve their efficacy as bone graft materials.

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Last Updated: Jun 24, 2026

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

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Published on: April 15, 2022

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

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Published on: September 11, 2015

Area of Science:

Biomaterials Science
Orthopedic Surgery
Materials Chemistry

Background:

Calcium phosphate (CaP) materials have been utilized as bone graft substitutes for approximately a century.
Extensive research over the past two decades has generated substantial data on the chemistry, in vitro characteristics, and biological properties of granular CaPs and CaP cement biomaterials.

Purpose of the Study:

To conduct an in-depth analysis of critical calcium phosphate cement (CPC) properties.
To identify strategies for significant advancements in the functional effectiveness of these biomaterials.

Main Methods:

Comprehensive literature review of CPC research.
Analysis of chemical, physical, and biological properties of CPCs.
Identification of key areas for property improvement.

Main Results:

Detailed examination of established CPC properties.
Highlighting of knowledge gaps and areas requiring further investigation.
Identification of specific material characteristics that influence in vivo performance.

Conclusions:

Further research into CPC properties is essential for enhancing their clinical application.
Strategic improvements in CPC formulation and characterization can lead to superior bone regeneration outcomes.
This analysis provides a roadmap for future innovations in calcium phosphate bone graft technology.