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A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

Stable angina and ST-segment depression: diagnostic value in patients undergoing coronary angiography

Bruno Ramos Nascimento1, Graziela Chequer, Marco Paulo Tomaz Barbosa

  • 1Serviço de Cardiologia do Hospital das Clínicas, Belo Horizonte, Brasil. ramosnas@uol.com.br

Revista Portuguesa De Cardiologia : Orgao Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology
|March 14, 2009
PubMed

Insights

Stable angina (SA) is a valuable marker for diagnosing coronary artery disease (CAD), especially in women. Exercise testing (ET) showed similar diagnostic value across sexes for CAD screening.

Area of Science:

  • Cardiology
  • Diagnostic Imaging
  • Clinical Medicine

Background:

  • Clinical history and exercise testing (ET) are primary methods for screening coronary artery disease (CAD).
  • Accurate interpretation of clinical data is crucial for effective CAD diagnostic and treatment strategies.

Purpose of the Study:

  • To evaluate the diagnostic utility of stable angina (SA) and ET in patients suspected of having CAD.
  • To compare the diagnostic performance of SA and ET between sexes in patients undergoing coronary angiography.

Main Methods:

  • Sixty-two patients undergoing coronary angiography were assessed.
  • Exercise testing (ET) was performed on 54 patients, with ischemia indicated by > or =1 mm ST-segment depression.
  • Coronary angiograms were analyzed, and patients were grouped by CAD severity: Group 1 (> or =70% stenosis) and Group 2 (<70% stenosis).

Main Results:

  • Stable angina (SA) demonstrated high specificity (91.7%) and positive predictive value (PPV) (80%) for CAD.
  • Exercise testing (ET) showed higher sensitivity (70.8%) but lower specificity (60%) compared to SA.
  • SA exhibited a significantly higher negative predictive value (NPV) and positive likelihood ratio (LR+) in women, indicating superior post-test prediction of angina in this group.

Conclusions:

  • Stable angina (SA) is a robust diagnostic marker for CAD, characterized by high specificity and PPV.
  • The diagnostic value of SA, particularly its NPV and LR+, is superior in women for predicting angina post-test.
  • Exercise testing (ET) yielded comparable results between sexes and aligned with established literature values for sensitivity and specificity in CAD screening.
Abstract

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