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Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
Published on: February 23, 2017
Whitening effect and morphological evaluation of hydroxyapatite materials
Alp Dabanoglu1, Claudia Wood, Franklin García-Godoy
1Ludwig Maximilians University, Faculty of Dentistry, Department of Operative Dentistry and Periodontology, Goethe Str. 70, D-80336 Munich, Germany.
American Journal of Dentistry
|March 14, 2009
Summary
Non-oxidizing nano- and micro-hydroxyapatite materials show promising whitening effects on tooth enamel. These materials offer a potential alternative to traditional oxidizing bleaching agents, with measurable color changes observed.
Area of Science:
- Dental Materials Science
- Biomaterials Engineering
- Cosmetic Dentistry
Background:
- Tooth whitening is a common cosmetic dental procedure.
- Oxidizing agents are traditionally used but can cause side effects.
- Hydroxyapatite (HA) is a key component of tooth enamel.
Purpose of the Study:
- To evaluate the whitening efficacy of non-oxidizing, non-acidic nano- and micro-hydroxyapatite materials on human enamel.
- To assess surface alterations on enamel following treatment with these HA materials.
Main Methods:
- Extracted caries-free human premolars were treated with various hydroxyapatite suspensions and polymer film mixtures.
- Simulated mechanical loading using hydrodynamic shear force was applied to the treated teeth.
- Tooth color changes (delta E) were measured using a dental spectrophotometer and analyzed statistically.
Main Results:
- Nano-hydroxyapatite, hydroxyapatite-nanocrystals, and tricalcium-phosphate groups showed statistically significant whitening effects (delta E).
- These changes were evident between baseline and post-hydrodynamic shear force application.
- No significant surface degradation was implied by the results.
Conclusions:
- Non-oxidizing nano- and micro-hydroxyapatite materials demonstrate significant whitening potential on dental enamel.
- These HA-based materials represent a promising, safer alternative to conventional oxidizing bleaching agents.
- Further research into these biomaterials for cosmetic dental applications is warranted.

