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Published on: August 1, 2025
Acute thrombosis after endarterectomy of stented left anterior descending artery
Tomoya Uchimuro1, Toshihiro Fukui, Wahei Mihara
1Department of Cardiovascular Surgery, Chiba Central Medical Center, Wakaba-ku, Chiba, Japan. tuchimuro@ccmc.seikei-kai.or.jp
Insights
Coronary endarterectomy complications include acute thrombosis. This case highlights successful recanalization of a thrombosed left anterior descending artery using a pacemaker, balloon pump, and anticoagulation.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Vascular Surgery
Background:
- Coronary endarterectomy is a surgical procedure to remove atherosclerotic plaque from a coronary artery.
- Acute thrombosis is a rare but serious complication following coronary endarterectomy.
- In-stent restenosis after stenting can necessitate complex interventions.
Observation:
- A 65-year-old male developed sick sinus syndrome and acute myocardial infarction three days post-coronary endarterectomy.
- The patient had a history of percutaneous stent implantation followed by endarterectomy with stent removal.
- Coronary angiography confirmed thrombosis at the reconstructed site of the left anterior descending artery.
Findings:
- The patient presented with acute myocardial infarction and sick sinus syndrome after coronary endarterectomy.
- Thrombosis was identified in the endarterectomized left anterior descending artery.
- A combination of pacemaker implantation, intra-aortic balloon pumping, and aggressive anticoagulation led to successful recanalization.
Implications:
- This case underscores the potential for acute thrombosis after coronary endarterectomy, even after prior stenting.
- Aggressive medical and mechanical support can achieve recanalization in complex thrombotic coronary events.
- Management strategies for post-endarterectomy thrombosis require prompt and multi-faceted intervention.
Abstract:
Acute thrombosis of the endarterectomized coronary artery is a serious complication after coronary endarterectomy. Herein, we describe a case of a 65-year-old man who had undergone percutaneous stent implantation in the left anterior descending artery, then after he received an endarterectomy with the removal of stents severe in-stent restenosis occurred. Three days after the operation, sick sinus syndrome developed with acute myocardial infarction. Coronary angiography revealed thrombosis at the reconstructed site of the left anterior descending artery. Pacemaker implantation, intra-aortic balloon pumping, and aggressive anticoagulation produced recanalization of the left anterior descending artery.
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