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Related Experiment Video

Updated: Jun 24, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Systemic lupus erythematosus with multiple lung cysts.

Ryo Maeda¹, Noritaka Isowa, Hiroshi Miura

¹Division of Thoracic Surgery, Matsue Red Cross Hospital, Matsue, Shimane, Japan. ryomaedamatsue@yahoo.co.jp

Interactive Cardiovascular and Thoracic Surgery

|March 14, 2009

Summary

This case study highlights a rare instance of recurrent pneumothorax in a woman with systemic lupus erythematosus (SLE) and multiple lung cysts. It underscores the unusual pulmonary complications that can arise from SLE.

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Area of Science:

Pulmonology
Rheumatology
Medical Case Reports

Background:

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect multiple organ systems.
Pulmonary manifestations are common in SLE, including pleuritis, pneumonitis, and pulmonary hypertension.
Cystic lung disease is an exceptionally rare complication of SLE.

Observation:

A 53-year-old non-smoking woman with a history of SLE since age 29 presented with recurrent spontaneous pneumothorax.
Chest computed tomography (CT) revealed multiple bilateral lung cysts.
The patient experienced sequential episodes of pneumothorax on the same side over two months.

Findings:

The case demonstrates a rare association between SLE, multiple lung cysts, and recurrent pneumothorax.
This presentation is unusual, as significant cystic lung disease is not a typical feature of SLE-related pulmonary involvement.

Implications:

This case expands the spectrum of known pulmonary complications associated with SLE.
It suggests the need for heightened awareness and investigation of cystic lung disease in SLE patients presenting with respiratory symptoms.
Further research may elucidate the specific mechanisms linking SLE to cystic lung development.