Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neuropeptides and nasal secretion.

J N Baraniuk1, M Kaliner

  • 1Department of Thoracic Medicine, National Heart and Lung Institute, London, United Kingdom.

The American Journal of Physiology
|October 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Allergic diseases in the new millennium. Introduction.

Postgraduate medicine·2009
Same author

Pharmacokinetics and tolerability of a new intravenous immunoglobulin preparation, IGIV-C, 10% (Gamunex, 10%).

Vox sanguinis·2003
Same author

A tender sinus does not always mean rhinosinusitis.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2002
Same author

Hypertonic saline nasal provocation and acoustic rhinometry.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2002
Same author

Nasal lavage concentrations of free hemoglobin as a marker of microepistaxis during nasal provocation testing.

Allergy·2002
Same author

Addition of intranasal glucocorticoids to standard antibiotic therapy for sinusitis.

Current allergy and asthma reports·2002

The nasal mucosa

Area of Science:

  • Neuroscience
  • Immunology
  • Rhinology

Background:

  • The nasal mucosa is innervated by sensory, parasympathetic, and sympathetic nervous systems.
  • Nociceptive sensory nerves trigger reflexes like sneezing and glandular secretion.
  • Sympathetic nerves regulate nasal patency through vasoconstriction.

Purpose of the Study:

  • To explore the neural regulation of the nasal mucosa.
  • To understand the roles of different nervous systems in nasal function and homeostasis.
  • To identify potential therapeutic targets for rhinitic diseases.

Main Methods:

  • Review of neuroanatomy and neurophysiology of the nasal mucosa.
  • Analysis of neurotransmitter roles in nasal responses.
  • Discussion of the balance between parasympathetic and sympathetic activity.

Related Experiment Videos

Main Results:

  • Sensory nerves initiate reflexes and release proinflammatory peptides.
  • Parasympathetic nerves cause vasodilation, increased permeability, and secretion.
  • Sympathetic nerves release vasoconstrictors, decompressing the mucosa.

Conclusions:

  • A balance between parasympathetic and sympathetic neurotransmitters maintains nasal homeostasis.
  • The nociceptive sensory system acts as a defense mechanism.
  • Neuropeptide modulation offers future treatment potential for rhinitis.