Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The sugared path to a normal lung: soluble beta-galactoside-specific lectins.

J T Powell1, F L Harrison

  • 1Department of Biochemistry, Charing Cross and Westminster Medical School, London, United Kingdom.

The American Journal of Physiology
|October 1, 1991
PubMed
Summary

Beta-galactoside-binding proteins in the lung regulate cell growth and RNA levels. These proteins, including a 14-kDa lectin and RL29, play crucial roles in lung physiology.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Value of risk scores in the decision to palliate patients with ruptured abdominal aortic aneurysm.

The British journal of surgery·2018
Same author

L-Serine-Mediated Neuroprotection Includes the Upregulation of the ER Stress Chaperone Protein Disulfide Isomerase (PDI).

Neurotoxicity research·2017
Same author

L-Serine: a Naturally-Occurring Amino Acid with Therapeutic Potential.

Neurotoxicity research·2017
Same author

Sex differences in mortality after abdominal aortic aneurysm repair in the UK.

The British journal of surgery·2017
Same author

Mapping the Workload Associated with Intact Abdominal Aortic Aneurysm.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2017
Same author

Meta-analysis of individual-patient data from EVAR-1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years.

The British journal of surgery·2017

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Pulmonology

Background:

  • Soluble beta-galactoside-binding proteins are a diverse family with varied biological roles.
  • These proteins are found in various tissues, including the lung, and are implicated in cellular functions.

Purpose of the Study:

  • To discuss the diverse functions of beta-galactoside-binding proteins within the lung.
  • To explore the roles of specific members, such as the 14-kDa lectin and RL29, in cellular regulation.

Main Methods:

  • Literature review and functional analysis of beta-galactoside-binding proteins.
  • Discussion of protein structure-function relationships, focusing on conserved domains.

Main Results:

  • The 14-kDa lectin acts as a negative modulator of cell growth.

Related Experiment Videos

  • RL29 is involved in regulating cytoplasmic RNA levels.
  • A subunit of the elastin receptor, a larger member, regulates elastic fibrillogenesis.

    • Conclusions:

    • Beta-galactoside-binding proteins possess diverse functions at the cellular level.
    • These proteins are likely critical for regulating overall lung physiology.
    • Homologous carboxy-terminal domains confer galactose-binding, while varied amino-terminal domains dictate specific biological functions.