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Related Concept Videos

Anthelminthic Agents01:15

Anthelminthic Agents

Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...
Hand hygiene01:23

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Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
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Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Electroconvulsive Therapy01:30

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early years,...
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Leishmaniasis is a widespread parasitic disease caused by several Leishmania species. It affects millions of people each year and remains a major public health problem in endemic regions. First-line treatment relies on pentavalent antimonials, including meglumine antimoniate and sodium stibogluconate. Even so, how these drugs work has not been fully clear, especially their interaction with parasite-specific biochemical pathways. One key target is trypanothione reductase (TR), an enzyme that...

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Updated: Jun 24, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Current treatments for pediculosis capitis.

Ian F Burgess1

  • 1Medical Entomology Centre, Insect Research and Development Limited, 6 Quy Court, Colliers Lane, Stow-cum-Quy, Cambridge, UK. ian@insectresearch.com

Current Opinion in Infectious Diseases
|March 14, 2009
PubMed
Summary

Head lice infestations are increasing, driving demand for new treatments due to insecticide resistance. Many popular alternative therapies lack robust evidence of effectiveness, requiring further investigation.

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Area of Science:

  • Dermatology and Public Health
  • Parasitology
  • Pharmacology

Background:

  • Rising prevalence of head lice (Pediculus humanus capitis) since the 1990s.
  • Insecticide resistance in lice populations necessitates novel therapeutic strategies.
  • Increased research interest in human louse infestation management.

Purpose of the Study:

  • To review current and emerging treatment options for head lice.
  • To evaluate the efficacy of various diagnostic and therapeutic methods.
  • To explore alternative therapies beyond traditional insecticides.

Main Methods:

  • Literature review of diagnostic criteria and treatment techniques for head lice.
  • Examination of evidence supporting alternative therapies, including plant-derived oils and physical methods.
  • Analysis of consumer perceptions regarding pesticide safety.

Main Results:

  • Many diagnostic methods for head lice lack proven efficacy.
  • Evidence supporting the effectiveness of popular alternative treatments is often limited or absent.
  • Plant-derived essential oils and physically acting preparations are explored as alternatives to pesticides.

Conclusions:

  • The efficacy of several popular head lice treatments requires deeper investigation.
  • Claims regarding the effectiveness of alternative therapies need rigorous scientific validation.
  • Further research is essential to identify reliable and effective treatments for head lice.