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Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
11:17

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Published on: October 12, 2012

[Heparin-induced thrombocytopenia]

Christina Christoffersen1, Stefan Lethagen, Jens Peter Gøtze

  • 1Klinisk Biokemisk Afdeling, Rigshospitalet, DK-2100 København Ø. christina.christoffersen@rh.regionh.dk

Ugeskrift for Laeger
|March 17, 2009
PubMed

Heparin treatment can cause an immune-mediated thrombocytopenia: HIT. HIT antibodies can be detected by various methods, but laboratory analyses are not specific or sensitive and may delay the diagnostic process. It is therefore important to initiate alternative treatment based on the clinical findings, and a clinical score system for evaluating the risk of HIT has been suggested. When HIT is likely, treatment consists of immediate replacement of heparin with alternative anticoagulation treatment and refrainment from warfarin therapy and platelet infusion.

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