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Updated: Jun 24, 2026

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

Lessons from VTE registries: the RIETE experience.

Manuel Monreal¹, Javier Trujillo-Santos

¹Department of Internal Medicine, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.

Best Practice & Research. Clinical Haematology

|March 17, 2009

Summary

Patients with cancer and venous thromboembolism (VTE) often face treatment challenges due to trial exclusions. The RIETE registry provides insights into managing VTE in cancer patients, informing real-world clinical practice.

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Published on: February 19, 2021

Area of Science:

Oncology
Hematology
Clinical Medicine

Background:

Venous thromboembolism (VTE) is a common complication in cancer patients.
Standard anticoagulant clinical trials often exclude these patients due to comorbidities and prognosis.
This exclusion limits the applicability of trial-based treatment guidelines to real-world cancer VTE cases.

Purpose of the Study:

To summarize key findings on the association between VTE and cancer from the RIETE registry.
To highlight the clinical management of VTE in cancer patients.
To inform treatment strategies for this vulnerable population.

Main Methods:

Prospective data collection in the 'Registro Informatizado de la Enfermedad TromboEmbólica' (RIETE) registry.
Inclusion of patients with symptomatic, objectively confirmed, acute VTE in Spanish hospitals since March 2001.
Analysis of published findings concerning VTE and cancer associations.

Main Results:

Cancer is a significant risk factor for VTE.
VTE in cancer patients is associated with increased morbidity and mortality.
Specific challenges in anticoagulation management for cancer patients are identified.

Conclusions:

Real-world data from registries like RIETE are crucial for understanding VTE in cancer.
Current treatment guidelines may need adaptation for cancer patients with VTE.
Further research is needed to optimize anticoagulation strategies for VTE in active cancer.