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Related Experiment Videos

Zygomycosis mimicking paranasal malignancy.

B E Akpunonu1, G Ansel, J D Kaurich

  • 1Department of Internal Medicine, Medical College of Ohio, Toledo.

The American Journal of Tropical Medicine and Hygiene
|September 11, 1991
PubMed
Summary

A rare case of zygomycosis in the maxillary sinus mimicked cancer in a healthy patient. Early nasal biopsy is crucial for accurate diagnosis and successful treatment with amphotericin B.

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Area of Science:

  • Mycology
  • Otolaryngology
  • Radiology

Background:

  • Zygomycosis, a rare fungal infection, can present insidiously.
  • Maxillary sinus lesions mimicking malignancy pose diagnostic challenges.

Observation:

  • A case of zygomycosis in the maxillary sinus of an immunocompetent patient is detailed.
  • Computed tomography revealed bony destruction, and histology confirmed fungal elements.
  • The presentation mimicked paranasal malignancy.

Findings:

  • Successful treatment involved both sinus irrigation and parenteral administration of amphotericin B.
  • Histopathological examination is key to differentiating zygomycosis from malignancy.

Implications:

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  • Radiologists and clinicians should consider zygomycosis in suspected sinus malignancies.
  • Prompt nasal biopsy is recommended for definitive diagnosis and appropriate therapeutic intervention.