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Related Experiment Videos

Axillary node dissection in malignant melanoma.

C P Karakousis1, W Goumas, U Rao

  • 1Department of Surgical Oncology, Roswell Park Memorial Institute, Buffalo, New York 14263.

American Journal of Surgery
|September 1, 1991
PubMed
Summary
This summary is machine-generated.

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Axillary node dissection for malignant melanoma has a 10% infection rate. Survival depends on node status, with negative nodes offering a 74% 5-year survival rate.

Area of Science:

  • Oncology
  • Surgical Oncology
  • Melanoma Research

Background:

  • Malignant melanoma treatment often involves axillary node dissection to assess and manage nodal metastasis.
  • Understanding the complications and prognostic factors associated with this procedure is crucial for patient outcomes.

Purpose of the Study:

  • To evaluate the complication rates of axillary node dissection in malignant melanoma patients.
  • To determine the prognostic significance of lymph node status on 5-year survival rates.

Main Methods:

  • Retrospective analysis of 261 axillary node dissections (212 initial, 49 repeat) in patients with malignant melanoma.
  • Data collection on wound infections, arm edema, and long-term survival based on lymph node characteristics.

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Main Results:

  • Wound infection occurred in 10% of cases; arm edema in 4% (2% permanent).
  • Five-year survival rates varied significantly with lymph node status: 74% for negative nodes, decreasing to 13% for fixed positive nodes.
  • Prognosis was poorer for palpable, larger, or fixed axillary lymph nodes.

Conclusions:

  • Axillary node dissection is associated with manageable complication rates.
  • Lymph node status, including size, palpability, and fixation, is a critical determinant of survival in malignant melanoma.