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Smoking cessation in chronic obstructive pulmonary disease.
Donald P Tashkin1, Robert P Murray
1Department of Medicine, David Geffen School of Medicine at UCLA, 37-131 Center for Health Sciences, 10833 Le Conte Avenue, Los Angeles, CA 90095-1690, USA. dtashkin@mednet.ucla.edu
Respiratory Medicine
|March 17, 2009
Summary
Smoking cessation is crucial for halting chronic obstructive pulmonary disease (COPD) progression. This review compares smokers with and without COPD, detailing effective strategies and therapies to aid long-term smoking cessation.
Area of Science:
- Pulmonology
- Addiction Medicine
- Public Health
Background:
- Chronic obstructive pulmonary disease (COPD) is a growing global health concern, projected to be the third leading cause of death worldwide.
- Cigarette smoking is the primary risk factor, accounting for 90% of COPD-related deaths.
- Many COPD cases remain undiagnosed due to a lack of awareness and simple spirometry testing.
Purpose of the Study:
- To compare the characteristics of smokers with COPD versus those without COPD regarding smoking behavior and cessation attempts.
- To review and discuss various strategies, including behavioral and pharmacological interventions, to improve long-term smoking cessation rates in COPD patients.
Main Methods:
- Literature review and comparative analysis of smoking behaviors in COPD patients versus non-COPD smokers.
- Summary and comparison of available and emerging smoking cessation strategies.
Main Results:
- Physician advice, especially when combined with "lung age" information, is a simple yet effective behavioral intervention.
- Pharmacological therapies like nicotine replacement, bupropion SR, and varenicline enhance quitting success.
- Novel nicotine vaccines are under clinical investigation as a future cessation aid.
Conclusions:
- Smoking cessation is the most effective intervention to slow or halt COPD progression.
- A combination of behavioral counseling and pharmacotherapy offers the best approach for achieving long-term smoking cessation in individuals with COPD.
- Further research into novel cessation methods like nicotine vaccines is warranted.
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