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Nodular cutaneous amyloidosis
H Trau1, D Shpiro, M Schewach-Millet
1Department of Dermatology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
The American Journal of Dermatopathology
|August 1, 1991
Abstract:
A nodular cutaneous amyloidosis biopsy specimen from a solitary nodule of a 75-year-old patient was characterized by amino terminal sequence analysis and was proved to be derived from immunoglobulin kIII light chain. Five years after the diagnosis of amyloidosis in the skin was made, a rectal biopsy demonstrated amyloid deposits in a blood vessel. It is suggested that nodular cutaneous amyloidosis is a slowly progressive systemic disease of the AL type, that manifest itself mainly in the skin.