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Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures ll: Types01:19

Seizures ll: Types

Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...

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Focal evolution following apparent interictal period on scalp electroencephalography in generalized epilepsy: a three-case study.

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Epilepsy associated with Graves' disease: Report of two cases.

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Related Experiment Video

Updated: Jun 24, 2026

Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury
09:16

Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury

Published on: June 21, 2019

Epileptic negative drop attacks in atypical benign partial epilepsy: a neurophysiological study.

Yoshiko Hirano1, Hirokazu Oguni, Makiko Osawa

  • 1Department of pediatrics, Tokyo women medical university, Shinjuku-ku, 162 Tokyo, Japan.

Epileptic Disorders : International Epilepsy Journal with Videotape
|March 17, 2009
PubMed
Summary

Drop attacks in atypical benign partial epilepsy (ABPE) are epileptic negative drop attacks originating from bilateral centro-temporo-parietal foci. These attacks involve proximal and axial muscles, differing from generalized epilepsy drop attacks.

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Last Updated: Jun 24, 2026

Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury
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Published on: June 21, 2019

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Published on: June 25, 2016

Area of Science:

  • Neurophysiology
  • Epileptology
  • Pediatric Neurology

Background:

  • Atypical benign partial epilepsy (ABPE) can present with complex seizure manifestations.
  • Understanding the neurophysiological underpinnings of drop attacks in ABPE is crucial for accurate diagnosis and management.

Observation:

  • A pediatric case of ABPE exhibiting focal motor seizures, epileptic negative myoclonus (ENM), and drop attacks was analyzed.
  • Video-polygraphic and computer-assisted back-averaging techniques were employed to study ENM and drop attacks.

Findings:

  • Episodic drop attacks and ENM were time-locked to centro-temporo-parietal (CTP) spike-and-wave complexes (SWC).
  • Drop attacks exhibited significantly larger SWC spike and slow-wave components compared to ENM episodes.
  • Short latencies were observed between SWC onset and the manifestation of ENM and drop attacks.

Implications:

  • Drop attacks in ABPE are characterized as epileptic negative drop attacks involving axial and proximal muscles.
  • These findings differentiate ABPE-related drop attacks from those seen in generalized epilepsies like Lennox-Gastaut syndrome.
  • This study provides insights into the specific neurophysiological mechanisms of drop attacks in ABPE.