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Intrathecal use of amikacin: a case report

L Barrou1, B Charra, A Hachimi

  • 1Reanimation Anaesthesia Department, Ibn Rochd University Hospital, Casablanca, Morocco.

The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases
|March 17, 2009
PubMed

Insights

Acinetobacter baumannii meningitis is rare, often hospital-acquired. This case highlights successful treatment of ventriculitis caused by A. baumannii using intravenous sulbactam and intrathecal amikacin.

Area of Science:

  • Neuroscience
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Meningitis caused by Acinetobacter baumannii is an uncommon hospital-acquired infection.
  • It predominantly occurs in patients following neurosurgical procedures.

Observation:

  • A 40-year-old male patient was admitted to the intensive care unit with subarachnoid hemorrhage.
  • The patient subsequently developed ventriculitis, a serious inflammation of the brain's ventricles.

Findings:

  • The ventriculitis was diagnosed as being caused by Acinetobacter baumannii.
  • Successful treatment was achieved with a combination of intravenous sulbactam and intrathecal amikacin.

Implications:

  • This case demonstrates an effective therapeutic strategy for rare Acinetobacter baumannii ventriculitis.
  • The findings support the use of combined antibiotic therapy in managing severe hospital-acquired brain infections.

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