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Protocol for Dengue Infections in Mosquitoes (A. aegypti) and Infection Phenotype Determination
15:25

Protocol for Dengue Infections in Mosquitoes (A. aegypti) and Infection Phenotype Determination

Published on: July 4, 2007

[Dengue in children: clinical and epidemiological characteristics, Manaus, State of Amazonas, 2006 and 2007]

Lúcia Alves da Rocha1, Pedro Luiz Tauil

  • 1Secretaria Municipal de Saúde, Manaus, AM. lucia.rocha@pmm.am.gov.br

Revista Da Sociedade Brasileira De Medicina Tropical
|March 17, 2009
PubMed

Insights

Dengue cases in Manaus children increased significantly from 2006 to 2007, with a rise in severe dengue forms. Despite more frequent hemorrhagic dengue, the overall mortality rate decreased.

Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Pediatrics

Context:

  • Dengue is a significant public health concern, particularly in tropical and subtropical regions.
  • Manaus, Brazil, experienced dengue outbreaks in 2006 and 2007.
  • Children are a vulnerable population during dengue epidemics.

Purpose:

  • To analyze the clinical and epidemiological characteristics of dengue in children in Manaus, Brazil.
  • To compare dengue case data between 2006 and 2007.
  • To identify trends in dengue severity and serotypes affecting children.

Summary:

  • The study analyzed 482 dengue cases in 2006 and 1,538 in 2007, sourced from the National System for Notifiable Diseases (SINAN).
  • A statistically significant increase in dengue cases among children under 15 and a rise in severe dengue forms were observed between 2006 and 2007.
  • While dengue hemorrhagic fever became more common in 2007, the mortality rate declined. Serotypes DEN-3 (2006) and DEN-1, DEN-2, DEN-3 (2007) were identified.

Impact:

  • Findings highlight an increasing burden of dengue in pediatric populations in Manaus.
  • The study underscores the importance of monitoring dengue trends and severity in children.
  • Results can inform public health strategies for dengue prevention and control in the region.

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