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Exercise training improves cutaneous microvascular endothelial function in post-surgical varicose vein patients
M Klonizakis1, G Tew, J Michaels
1Sheffield Vascular Institute, Northern General Hospital, Herries Road, Sheffield, S5 7AU, UK.
Microvascular Research
|March 18, 2009
Summary
Treadmill walking exercise improved blood flow in the skin's small blood vessels for patients recovering from varicose vein surgery. This exercise intervention enhanced microvascular endothelial vasodilator function after surgery.
Area of Science:
- Vascular Biology
- Exercise Physiology
- Post-Surgical Recovery
Background:
- Varicose vein surgery can impact microvascular function.
- Restoration of vascular health is crucial for patient recovery.
Purpose of the Study:
- To investigate the effects of exercise training on cutaneous microvascular function in post-surgical varicose vein patients.
- To determine if treadmill walking can improve endothelial function in the lower limbs.
Main Methods:
- 16 post-surgical varicose vein patients were randomized into an exercise or control group.
- The exercise group underwent 8 weeks of twice-weekly treadmill walking.
- Cutaneous microvascular function was assessed using laser Doppler flowmetry and iontophoresis of acetylcholine chloride and sodium nitroprusside.
Main Results:
- Exercise training significantly increased peak vasodilator responses to acetylcholine in the supine position (P=0.03).
- A similar positive trend was observed in the standing position (P=0.08).
- No significant changes were found in the control group or for responses to sodium nitroprusside.
Conclusions:
- Moderate-intensity lower-limb exercise training improves microvascular endothelial vasodilator function in post-surgical varicose vein patients.
- Exercise may be a beneficial component of recovery after varicose vein surgery.
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